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  • Cagrilintide

    Cagrilintide

    Weight loss.  Operates on different receptors than semaglutide or tirzepatide, so is often stacked with one of them.  It activates central amylin receptors to promote satiety, slow gastric emptying, and reduce food intake.  Cagrilintide plus semaglutide is called CagriSema.  CagriSema is in clinical trial by Novo.

    Dosage: Weekly. If stacked with another GLP-1, dose it at about 1/4 the dosage of the other.  For example, 8mg of Tirzepatide (or Retatrutide) would be stacked with 2mg of Cagrilintide.
    10mg vial with 2cc BAC = 20 units per mg.
    12.5mg vial with 2.5cc BAC = 20 units per mg.