Peptides A-L, by Nevin Pratt

AOD-9604

Weight loss.  Bone and cartilage regeneration. Boosts metabolism. 

This peptide possibly aids in the prevention and possible treatment of osteoporosis, through direct action on osteoblasts, the cells which build new bone.   Also, many clinics combine it with hyaluronic acid injections, because studies show AOD-9604 aids in cartilage regeneration.  Among other uses, I recommend this peptide after any PRP, Stem Cells, or Exosomes treatments.

AOD-9604 is the synthesized fragment of human growth hormone (specifically it's the last 15 molecules on the chain).  Half life 8-10 hours.  AOD-9604 doesn't down-regulate your own endogenous growth hormone production like HGH injections will.

If you have stalled on a GLP-1 (tirzepatide, retatrutide), then AOD-9604 is very effective at breaking the stall.  It also helps reduce visceral fat.

There's a study in Growth Hormone and IGF Research that shows AOD-9604 significantly up-regulates the production of chondrocytes, which are the only cells in your body that can produce cartilage. It has been shown to stimulate the synthesis of cartilage type 2 and aggrecan, which means it might help you avoid a knee replacement! 

More info on AOD-9604 can be found here:
https://www.peptidesciences.com/peptide-research/category/aod-9604-articles

That article recommends BPC-157, AOD-9604, and MOTS-c for bone mineral density improvement.

Dosage: 2-3 times per day. 250-600mcg per day.  Before eating, and before exercise.

6mg vial, with 3cc BAC = 300mcg per 15 units, or 250mcg per 12.5 units.
With 2.5cc BAC = 250mcg per 10.4 units, 300mcg per 12.5 units.
I recommend 2.5cc BAC and then pull 10-12 units.

BPC-157

Soft tissue injury repair.  Half life 6-8 hrs.  Local injection at an injury site is best, but systemic (in the stomache area) works quite well too. People often mix this with TB-500 in the same vial, but I recommend against that.  Those two peptides have a different PH and a different half life.  Also different optimal dosing schedules.  Keep them separate.

A study on using BPC-157 for regeneration can be found here.

Here are a couple of Youtube short videos on it.  The first is a Joe Rogan interview, and the second is from a well-known Stanford University professor, Dr. Andrew Huberman:

https://www.youtube.com/shorts/EVejn72GgQo
https://www.youtube.com/shorts/kOUvJVD_78U

Dr. Trevor Bachmeyer calls it a "forever peptide", to be taken daily, and talks extensively about BPC-157 in this video:

https://youtu.be/nRi9GqTfGqY?si=bh2tuRTmX64_awQW

Here are some studies on it:

https://pubmed.ncbi.nlm.nih.gov/34267654/
https://pubmed.ncbi.nlm.nih.gov/40756949/

Dosage: 300mcg to 600mcg daily.  
5mg vial with 2cc BAC = 20 units daily = 500mcg/dose.
10mg vial with 2cc BAC = 10 units daily = 500mcg/dose.
10mg vial with 3cc BAC = 10 units for 333mcg.

If your kangaroo can tolerate daily injections, then inject BPC-157 daily, and TB-500 every 3 to 5 days.

DSIP

A 9-amino acide peptide named by Swiss researchers in the 1970's as "Delta Sleep Inducing Peptide".  

DSIP-like material has been found in human brain, plasma, pituitary tissue, and even breast milk, which strongly suggests it’s part of our endogenous physiology.  It touches the hypothalamus and pituitary, tweaks stress hormones like ACTH and cortisol, nudges luteinizing hormone and growth hormone, and influences neurotransmitters tied to stress, mood, and pain.  Because of all that it does, current researchers seem to refer to it less as a sleep inducer and more as a circadiam rhythm peptide that just happens to help with sleep.

In a chronic pain pilot study, 6 out of 7 patients with things like migraines, psychosomatic pain, and tinnitus-associated pain had significant pain reduction after DSIP therapy. Many of these cases were long-standing and hard to treat. Their depressive symptoms improved alongside the pain.

In small insomnia trials (including a multi-study series by Schneider-Helmert and colleagues), insomniacs given DSIP for a few nights saw complete normalization of sleep patterns. Sleep architecture returned to the range seen in people without insomnia after just four nights of treatment. No next-day hangover and actually better daytime alertness and cognitive performance than placebo.

Dosage: 100-500mcg daily.
5mg vial 2cc BAC, 20 units = 500mcg

Epitalon / Epithalon

Increase telomerase length.  May help prevent or delay cognitive decline.

Dosage: 5-10mg per day, 5 days per week, 2 to 3 weeks per cycle, two or three cycles per year. Any time.
50mg vial with 2cc BAC, 20 units daily = 5mg per dose.
10mg vial with 2cc BAC, 40 units = 2mg

Glutathione

Antioxidant, detoxification, immune support, reduction of inflamation. Fertility support (increases sperm motility).

Glutathione is a tripeptide, but functionally it’s the master antioxidant and the liver’s lead janitor.  Every time you burn fat, process alcohol, or deal with environmental toxins, your liver is cranking through oxidative stress. Without enough glutathione, that stress turns into damage.

It helps clear toxins released by shrinking fat cells, supports mitochondrial function, and keeps your liver membranes, DNA, and enzymes protected while the heavy lifting is done.

Research has shown that natural glutathione levels decline with age, which may increase cellular vulnerability to oxidative stress. Because of these broad protective functions, glutathione is considered essential for sustaining healthy mitochondrial activity and overall cellular homeostasis.

Glutathione works just like American Wellness advertises.  However...

I prefer injectable Glutathione over an IV push.  It is faster and more convenient to administer, and I can custom tailor the dose (I choose lower dosages done more frequently).  It is also cheaper, at only a few dollars per 100mg injection.

I split the 600mg dosage that American Wellness does into 100mg doses, taken as needed, but at most twice weekly for two weeks.  If I do a two week schedule, it is a micro-dosing schedule done over two weeks instead of a sudden 600mg blast you would get from American Wellness. 

To get a 100mg dose, I mix 3cc of bacteriostatic water with a 600mg vial of Glutathione.  This yields a 100mg dose @ 50 units (1/2 cc), pulled via an insulin syringe.

Glutathione injection should be intramuscular (into muscle), whereas most peptides are injected subcutaneous (into fat).  I prefer my thigh.

I will use glutathione if I am feeling worn out, sore, and tired, and I can't seem to kick the feeling with more sleep, rest, and/or exercise.  I find a glutathione shot to be a better pain reliever and muscle relaxer than Tylenol®, and it wakes me up like a splash of cold water.

Shortly after injection, I get a warm tingly sensation all over my body.  Then over the next hour or two, an obvious diminishment of soreness (inflamation), and a wide-awake feeling.

Dosage: 100mg to 200mg per dose, every other day, until max of 600mg to 1200mg. Any time. 
600mg vial with 3cc BAC, 50 units per dose = 6 doses of 100mg each. 

Ipamorelin

Ipamorelin is a GH releasing peptide. Stimulates Ghrelin (makes you hungry). Half life 2-3 hours.  If you instead want a GH releasing peptide that doesn't stimulate ghrelin, use Tesamorelin.

Pair this with CJC-1295. Do not take one without the other.

They are both GH releasers, but along different pathways, and very synergistic with each other.

Dosage:  

• Anti-aging & wellness:
  200–300 mcg per day, typically in one or two doses.

• Muscle growth or fat loss:
  300–500 mcg per day, with dosing split into AM and PM injections for more stable GH release.

KPV

Skin health, psoriasis, eczema.  Wound healing (a bit like BPC-157).  Reduces inflamation.

Referred by some doctors as "The Greatest Anti Inflammatory Ever".

Inflamed and damaged tissues are always pumping out "signals" (certain proteins). Those tissues upregulate certain transporters and exhibit increased vascular permeability. In other words, the inflamed tissue is screaming with biochemical distress signals.  KPV is drawn to those areas like a magnet, and in doing so, finds and targets the inflamed tissue specifically, regardless of where you initially injected the KPV.  Healthy normal tissue doesn't even see the KPV, while the damaged tissue is flooded with it.

A Journal of Pharmacology in Experimental Therapeutics study used a model with two groups of mice with Colitis.  One group was given subq injections of KPV, while the control group got Saline injections. The KPV group had dramatic reductions of the disease, and inspection of the colon tissue showed massive protection, with no inflammatory cells, and almost zero ulceration.  Also showed reduced clinical severity of arthritis, and CT scans showed profound reduction in bone erosion.

Helps with psoriasis, which is an inflammatory-driven condition that KPV helps reduce or eliminate.

Dosage: 100-500mcg, one to two times per day.  Systemically works well, but locally at the problem site is better. 
10mg vial with 2.5cc BAC, 10 units = 400mcg.
12.5mg vial with 2.5cc BAC, 10 units = 500mcg.